Thoracic/Respiratory

  • Disorders of Pleura, Mediastinum, and Chest Wall
    • Costochondritis
    • Mediastinitis
    • Pleural Effusion
    • Pleuritis
    • Pneumomediastinum
    • Pneumothorax
    • Empyema
  • Acute Respiratory Distress Syndrome (ARDS)
  • Obstructive/Restrictive Lung Disease
    • Asthma/Reactive Airway Disease
    • Bronchitis
    • Bronchopulmonary Dysplasia
    • Chronic Obstructive Pulmonary Disease (COPD)
    • Cystic Fibrosis
    • Environmental/Industrial Exposure
    • Bronchiolitis
  • Physical and Chemical Irritants/Insults
    • Pneumoconiosis
    • Toxic Effects of Gases, Fumes, Vapors
  • Pulmonary Embolism
    • Septic Emboli
    • Venous Thromboembolism
    • Massive and Submassive Embolism
    • Fat Emboli
  • Pulmonary Infections
    • Lung Abscess
    • Pneumonia
      • Aspiration Pneumonia
      • Comunity-Acquired Pneumonia (CAP)
      • Healthcare-Associated Pneumonia (HAP)
      • Pneuocystis
      • Pulmonary Tuberculosis
      • Respiratory Syncytial Virus (RSV)
      • Pertussis
    • Pulmonary Tumors
    • Pulmonary Hypertension


Asthma Exacerbation

Rapid Review

  • Background
    • Diffuse airway inflammation characterized by bronchial hyperresponsiveness and reversible airflow obstruction.
    • Acute exacerbations can be caused by viral infections, allergens, tobacco, or emotional factors
  • Signs/Symptoms
    • Dyspnea, cough, chest tightness. May present in respiratory failure.
    • (+) expiratory wheezing, (+) tripod positioning
  • Diagnosis
    • Clinical diagnosis in emergency setting
    • Formal diagnosis made with spirometry
  • Treatment
    • Nebulizers (albuterol/ipratropium), steroids, +/- magnesium, +/- epinephrine.
    • May require NIPPV or intubation
  • Disposition
    • Admit patients who continue to be tachypnic or hypoxic despite treatment (floor, observation, or ICU depending on severity).
    • Patients who respond well to treatment can be discharged after a brief observation to ensure stability.

Pearls

  • Be aggressive early in the management of asthma. Consider the use of epinephrine, similar to how you would use it with anaphylaxis.
  • Due to it bronchodilatory effects, ketamine is the induction agent of choice for intubating asthmatics. 
Video Credit: Osmosis


Pleural Effusion

Rapid Review

  • Background
    • Accumulation of excess fluid between the pleural space outside of the lungs.
    • May be transudative (due to fluid shifts) or exudative (due to infection, malignancy, etc.)
  • Signs/Symptoms
    • Dyspnea, pain with inspiration
    • (+) decreased breath sounds, (+) decreased tactile fremitus, (+) dullness to percussion
  • Diagnosis
    • CXR (shows blunting of costophrenic angle). Chest CT/US can also be used.
    • Thoracentesis is the gold standard. Light criteria used to differentiate transudative vs exudative effusion.
  • Treatment
    • Thoracentesis or tube thoracostomy (depending on size and etiology)
    • Diuresis helpful if due to CHF 
  • Disposition
    • Discharge is appropriate if patient is stable and the source of the effusion is known and being treated. Should have close follow-up.
    • Admit patients with unknown sources or empyema. ICU is required for hemodynamically unstable.

Pearls

  • In general, bilateral effusions tend to be from a transudative process (ex. CHF, cirrhosis) Unilateral effusions tend to be from an exudative process (ex. Infection, cancer, pancreatitis, etc.). 
  • Ultrasound is a useful adjunct for both identifying pleural effusions and reducing the risk of complications during thoracentesis.
Video Credit: Pleural Effusion


Pneumonia (Bacterial)

Rapid Review

  • Background
    • Acute inflammation of the lungs caused by bacterial infection (typically S. pneumonia)
  • Signs/Symptoms
    • Symptoms: Fever/chills, cough, dyspnea, rigors, pleuritic chest pain
    • Signs: Rust-colored sputum, tachycardia, rales/rhonchi
  • Diagnosis
    • Clinical findings, (+/-) CXR
  • Treatment
    • Antibiotics
      • Outpatient (doxycycline or azithromycin)
      • Inpatient (Ceftriaxone + azithromycin or fluoroquinolone)
  • Disposition
    • Patients < 65 years old who appear well and have access to PCP follow-up within 72 hours can be safely discharged.
    • Admit anybody who doesnโ€™t fit the above criteria. ICU if hemodynamically unstable.

Pearls

  • The CURB-65 and the Pneumonia Severity Index are both available clinical scoring systems that can aid with disposition decisions.
  • Always consider pneumonia in patients presenting with suspected exacerbation of underlying diseases (ex. Asthma, COPD, CHF)

Deep Dive

Video Credit: Strong Medicine


Pneumothorax

Rapid Review

  • Background
    • Accumulation of free air in the pleural space, causing partial or complete collapse of the lung.
    • Can be spontaneous (blebs, COPD, TB), iatrogenic (central line, thoracentesis), or traumatic (blunt/penetrating trauma)
  • Signs/Symptoms
    • Symptoms: dyspnea, ipsilateral chest pain
    • Signs: (+) hyperresonance, (+) diminished breath sounds, (+) decreased tactile fremitus
  • Diagnosis
    • CXR (absent lung markings along periphery)
  • Treatment
    • Small pneumothorax (<15%) can be observed
    • Large pneumothorax (>15%) require thoracostomy
  • Disposition
    • Patients with resolution from spontaneous pneumothorax following treatment may be discharged with follow-up in 24-48 hours
    • Admit patients with tension pneumothorax or those requiring a chest tube.

Pearls

  • Stardard IV angiocatheters are too short to adequately penetrate the pleural cavity, especially in larger framed individuals. Use pneumothorax specific catheters when possible. 
  • JVD, hypotension, and tracheal deviation are late signs of tension pneumothorax. Do not wait for these signs to initiate treatment. 
Video Credit: Osmosis


Pulmonary Embolism

Rapid Review

  • Background
    • Occlusion of pulmonary arteries by thrombi that typically originate from the lower extremities or pelvis
  • Signs/Symptoms
    • Symptoms: Dyspnea (most common), pleuritic chest pain, syncope
    • Signs: (+) tachypnea, (+) tachycardia, (+) hypotension
  • Diagnosis
    • CT PE is the gold standard
    • CXR may show โ€œwestermark signโ€ or โ€œHampton humpโ€
  • Treatment
    • O2, anticoagulation (heparin, LMWH), hemodynamic support (fluids, pressors)
    • Thrombolytics for unstable patients. 
  • Disposition
    • Most patients with PE will be admitted. ICU if high risk for hemodynamic collapse.
    • Patients who are low risk and do not have right heart strain may be considered for discharge on anticoagulation and close follow-up.

Pearls

  • EKG findings (ex. tachycardia, new T wave inversions, rightward axis) cannot definitively rule in/rule out pulmonary embolism, but may help push you to search for it. 
  • A V/Q study is a reasonable alternative for pregnant patients, but tends to take longer and is less valuable in determining alternative etiologies.
Video Credit: Strong Medicine